Gentamicin-resistant enterococci and endocarditis.
نویسندگان
چکیده
منابع مشابه
Gentamicin-resistant enterococci and endocarditis.
We report a case of endocarditis associated with a highly gentamicin-resistant enterococcus that failed to respond to conventional antibiotic combination therapy. Clinical resolution was achieved following cardiac surgery and antimicrobial treatment dictated by in vitro testing of the patient's organism. Laboratories should test blood culture isolates of enterococci for high level gentamicin re...
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~ihu1~Ul ampicillin l'U"::: 8 fl1lJlIYI'U penicillin G. m"l~ trough II"::: peak serum bactericidal 1~fh <1: 2 II"::: 1: 16 ~llJlil~lJ. m.,MH'ihu1lJU.,:::YI1'UUl ofloxacin l'U"::: 900 lJfl. 't'll1,.r":::~lJ trough , ~ ~ . 'd I ., oil il "'_'I 1"', ~ I ~ II"::: peak serum bactenci a l~lJ'U'UlJ11 'U 1: 2 II"::: 1: 64. HulU ~UltlU'Ul'U 4 lfu~l'l1I1":::'I1lU "'" ~ cu., _I "'lIto <f, .lSi , 91_'1 1i1...
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Carbenicillin and gentamicin were tested for synergism against 25 strains of enterococci by two different methods. Killing curves were determined by doing serial colony counts of broth cultures containing the antibiotics separately and in combination. The combination was synergistic for all 25 strains with 75 and 4 mug of carbenicillin and gentamicin per ml, respectively. Reducing the concentra...
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Strains of enterococci isolated from 34 patients were studied for susceptibility to oxacillin and gentamicin alone and in combination. The minimal bactericidal concentrations of oxacillin and gentamicin for these strains ranged from 16 to 250 mug/ml (median 32 mug/ml) for oxacillin and 12 to 48 mug/ml (median 24 mug/ml) for gentamicin. The minimal bactericidal concentration of oxacillin for 50%...
متن کاملSynergism of cefazolin-gentamicin against enterococci.
A miniaturized technique for detecting antibiotic synergy by using microliter volumes was perfected. With this microtiter serial dilution method, the effect of the previously untried combination of cefazolin and gentamicin on 10 strains of enterococci was evaluated. At clinically achievable concentrations, the combination of cefazolin and gentamicin was found to be synergistic against all 10 st...
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ژورنال
عنوان ژورنال: Postgraduate Medical Journal
سال: 1989
ISSN: 0032-5473
DOI: 10.1136/pgmj.65.764.390